Abiraterone Acetate Tablet castration resistant metastatic prostate cancer and how does help in its treatment?
Castration resistant prostate cancer, as the name itself suggests is a dreaded form of cancer that is in the incurable stage, and usually continues to metastasize in 90% of the cases. Due to this cancer, patients can experience fractures, compression of the spine, skeletal deformities and severe pain. The treatment of cancer at this stage is resistant to surgical removal and therefore, a hormone deprivation or androgen deprivation that blocks the effect of testosterone is prescribed to people with this cancer. Abiraterone Acetate Tablets contains androgens to block androgen receptors or render the chemical pathways that render androgen in the body and hence is extremely helpful in preventing the spread of the disease.
What are Abiraterone Acetate Tablets?
Abiraterone Acetate Tablets more commonly known by its brand name Generic Zytiga is an anti androgen medication that is commonly prescribed to treat conditions of prostate cancer. Argentinians are those medicines which are androgen antagonists or testosterone blockers ensuring that the biological effect of these hormones is not felt by the body.
Abiraterone Acetate works in a similar manner by blocking androgen receptors or blocking the biochemical pathways that enable androgen production in the body. Abiraterone acetate generic inhibits CYP17 (17α-hydroxylase/C17,20-lyase). It is a whitish crystalline powder and is mostly insoluble in water. It is most commonly prescribed to patients with metastatic-castration resistant prostate cancer (CRPC) which is an extremely virulent and hard to treat form or cancer, or metastatic high-risk castration sensitive prostate cancer making it an extremely powerful drug for those patients with high-risk prostate cancer.
Abiraterone Generic Availability in the market for the treatment of metastatic high-risk prostate cancer
Zytiga is an extremely common brand name in the treatment of high-risk metastatic cancer in the market today. It is usually stored between the temperatures of 20-25* C and kept out of reach of children and infants to prevent accidental consumption. Abiraterone Acetate is usually available only through prescription and is commonly available throughout the world. It is not an “over the counter” medication. Now, with a legitimized prescription, patients may be able to “buy abiraterone online” in certain countries, or in certain states in the United States. As country wise medical regulatory laws differ, it may help to verify in your country as to whether Zytiga may be purchased online with a valid prescription.
Below are mentioned some generic option of Abiraterone (Zytiga):
Abiraterone Acetate is a powerful and effective option. But is it economical?
“Abiraterone price in the USA” can go up to an average of five thousand dollars a month. While seeming pricey, it is usually covered under a valid health insurance plan in the United States and therefore patients seeking treatment for high-risk castration resistant metastatic prostate cancer are advised to seek the guidance of their medical practitioner to prescribe a tablet that is covered by their health insurance plans.
Abiraterone cost in India
The cost of Abiraterone in India or the price of generic Zytiga in India is much more economical and affordable for the patients. In India, the price of Abiraterone Acetate usually is about Rupees 200 per tablet. Depending on the dosage requirements and the needs of the customer, Zytiga tablets are available in a variety of sizes and are therefore extremely easy to procure. For hospitals and establishments requiring large sizes of Zytiga, it is also available in bulk ensuring that it is perpetually available to those who need the drug.
Abiraterone Acetate Tablets are usually covered by insurance companies for those patients with a valid health insurance. For instance, in Australia, Zytiga is commonly available under the Pharmaceutical Benefits scheme which covers high-risk prostate cancer.
History of Abiraterone Acetate in the treatment of High-risk castration resistant metastatic cancer
Developed in the early 1990’s by Mike Jarman, Elaine Barrie, and Gerry Potter in the Institute of Cancer research in London, Abiraterone was developed as a nonsteroidal androgen synthesizing inhibitor to treat prostate cancer. The developers filed a patent which was followed by the commercialization of the drug and availability to the common public which was first licensed to BTG, which further licensed to Cougar Biotechnology which was acquired by Johnson and Johnson. Currently, Abiraterone is commonly found under the brand name Zytiga, marketed by Janssen Biotech, a subsidiary of Johnson and Johnson.
R&D and alternative uses of Abiraterone Acetate for treatment of other cancers and hyperplasia
Currently, Zytiga or Abiraterone Acetate Tablets is also being research and developed for the possibility of its usage in the treatment of breast cancer and ovarian cancer with the medicine in phase II of the clinical trial for these diseases. It is also being considered for the treatment of congenital adrenal hyperplasia, but currently not being pursued extensively.
Abiraterone price in India
Those who are unfortunately afflicted with metastatic high-risk castration resistant prostate cancer are advised to seek medical attention immediately and discuss the possibility of the usage of Abiraterone Acetate Tablets in their treatment plan if the drug is found suitable and per the needs of the patient in question. Abiraterone is also generally considered a low-risk drug in the treatment of high-risk cancer in comparison to the alternatives that were previously available in the market. By the use of Abiraterone Acetate Tablets, it has been estimated that a significant proportion of people who were diagnosed with metastatic high-risk castration resistant cancer either completely resistant or relatively resistant have shown positive signs of recovery post the administration of Abiraterone Acetate. It is advised to consult the nearest physician to discuss the administration of Abiraterone Acetate if you think you might need it.